Basic Fexofenadine Information

• INN (International Nonproprietary Name): Fexofenadine
• Brand names available in Canada: Allegra, Apo-Fexofenadine
• ATC Code: R06AX26
• Forms & dosages: Tablets (60mg, 120mg)
• Manufacturers in Canada: Sanofi, Dr. Reddy's, Teva Pharma
• Registration status in Canada: Approved for OTC use
• OTC / Rx classification: Available over-the-counter

Latest Research Highlights

Recent clinical trials examining the effectiveness of fexofenadine have revealed its strong performance in treating allergic rhinitis and chronic urticaria. Studies conducted in Canada and internationally from 2022 to 2025 report a high satisfaction rate among patients experiencing symptom relief. Research published in *The Canadian Journal of Clinical Pharmacology* determined that a dosage of 180mg administered once daily is effective in managing symptoms. This regimen has notably decreased the need for adjunct therapies, which is an encouraging finding for health professionals and patients alike. To further highlight the data, key findings from various studies can be summarized in tables that differentiate dosages and effectiveness based on demographics, including age groups such as children and adults. Additionally, long-term safety assessments have strengthened fexofenadine's reputation as a preferred antihistamine option. As a result, it has secured approval from Health Canada for both prescription (RX) and over-the-counter (OTC) sales, solidifying its role in allergy management.

Clinical Effectiveness in Canada

Health Canada has recognized fexofenadine as a first-line treatment for allergic rhinitis and chronic urticaria. The drug’s monographs confirm its safety profile, ensuring adherence to the Drug Identification Number (DIN) system. This system guarantees brands like Allegra and Apo-Fexofenadine comply with national health regulations. Availability has been further enhanced by including fexofenadine in provincial drug plans, such as Ontario's Drug Benefit and BC PharmaCare, facilitating easier access for Canadians. A table detailing DIN numbers, alongside recommendations for fexofenadine usage across provinces, serves as an essential guide for healthcare providers. Clinical outcomes indicate significant improvements in the overall quality of life for patients. Evidence suggests that fexofenadine has a markedly lower incidence of sedation compared to first-generation antihistamines, which makes it a safer choice for populations that need to avoid drowsiness, such as the elderly.

Indications & Expanded Uses

Fexofenadine is FDA-approved for managing seasonal allergic rhinitis and chronic idiopathic urticaria. However, its off-label uses in Canada have gained attention. Clinicians have reported favorable outcomes in treating other conditions, such as atopic dermatitis and eczema, though these uses have limited formal recognition. For clarity, key indications can be defined as follows:

• Seasonal Allergic Rhinitis: Relief from sneezing, runny nose, and itchy eyes.
• Chronic Urticaria: Management of skin hives and itching.

While off-label prescriptions should be approached with caution, anecdotal evidence and patient forums suggest effectiveness, especially for those with comorbid conditions. Recognizing the difference between approved and off-label uses is vital for both healthcare providers and patients, aiding informed decision-making. By enhancing awareness of these applications, healthcare practitioners can help drive better health outcomes for Canadians who are seeking relief from allergies beyond conventional treatments.

Composition & Brand Landscape

Fexofenadine is a popular antihistamine available in Canada as Allegra and Apo-Fexofenadine, with options in 60mg and 120mg strengths. These products primarily contain fexofenadine hydrochloride as the active ingredient, recognized for its effectiveness in alleviating allergic reactions.

Brand Name	Available Doses	DIN Reference
Allegra	60mg, 120mg	DIN available upon inquiry
Apo-Fexofenadine	60mg, 120mg	DIN available upon inquiry

Even though brand-name products are widely known, generic options provide an affordable alternative, particularly under provincial health plans. Pharmacies like Shoppers Drug Mart and Rexall facilitate easy access, ensuring patients can choose according to their financial and therapeutic needs.

Understanding the composition of fexofenadine is crucial for patient education. It encourages conversations regarding other therapeutic alternatives and highlights its safety profile compared to older antihistamines. This knowledge empowers healthcare professionals and patients alike, ensuring informed decisions about allergy management.

Contraindications & Special Precautions

While fexofenadine is generally well-tolerated, certain contraindications warrant attention, particularly for Canadian healthcare professionals. Absolute contraindications include known allergies to fexofenadine or its excipients. Relative contraindications involve cautious use in individuals with renal impairment or among elderly patients, given the increased risk associated with polypharmacy.

• Absolute Contraindications:
  • Known allergy to ingredients
• Relative Contraindications:
  • Renal impairment (consider dose modifications)
  • Older adults (caution required)

Health warnings from Health Canada highlight the need for careful use in pregnant or breastfeeding individuals, emphasizing that fexofenadine should only be used when clearly necessary. Addressing these considerations is essential for vulnerable populations, guiding safe and effective treatment pathways.

Dosage Guidelines

In Canada, fexofenadine is typically prescribed for allergic rhinitis and chronic urticaria. The standard dosages are straightforward: adults usually take 120mg once daily, while children aged 6 to 11 are recommended to have 30mg twice daily. For children aged 2 to 5, a liquid formulation is typically preferred.

Age Group	Recommended Dose
Adults	120mg once daily
Children (6-11 years)	30mg twice daily
Children (2-5 years)	Liquid formulation advised

When considering renal impairment, dose adjustments may be necessary. Health authorities recommend continuous use of fexofenadine during allergy seasons to achieve optimal outcomes. Detailing clear dosage schedules, especially for pediatric patients, enhances treatment adherence and ultimately improves health outcomes in the community.

Interactions Overview

Fexofenadine is celebrated for its minimal drug interaction profile, making it a preferred option in Canadian pharmacotherapy. However, being aware of its potential interactions is essential for patients aiming for optimal therapeutic outcomes.

Consuming acidic beverages, particularly citrus juices such as orange or grapefruit juice, can significantly reduce fexofenadine absorption. Patients should consider the following common interactions:

• Food Interactions: Citrus juices (reduces absorption)
• Medication Interactions: Antacids containing aluminum or magnesium (take separately)
• Other central nervous system depressants (increased sedation risk)

Health Canada has identified several drug combinations that may complicate treatment, especially for patients managing coexisting conditions. By educating patients about these interactions, they can participate more actively in their treatment decisions, prompting meaningful conversations with healthcare providers.

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Cultural Perceptions & Patient Habits

In Canada, perceptions of fexofenadine are shaped by community health approaches and collective experiences. Engaging in online communities such as Reddit Canada and Facebook health groups reveals insights into personal experiences with fexofenadine, yielding anecdotal data that highlights its benefits.

Differences in pharmacy access between urban and rural areas play a significant role in treatment choices. Urban residents often enjoy an array of over-the-counter medication options, while those in rural areas may rely on nearby pharmacies like Shoppers Drug Mart or London Drugs.

Discussion forums indicate a common appreciation for the non-drowsy nature of fexofenadine, especially when compared to older antihistamines, which are often seen as a last resort due to their sedation effects. Promoting community discussions about antihistamine use fosters better health literacy, supportive decision-making, and improved health outcomes across Canada.

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Availability & Pricing Patterns

Fexofenadine is readily available in pharmacies throughout Canada, including major chains such as Rexall, Jean Coutu, and Shoppers Drug Mart. Price variations exist based on location and whether the patient is purchasing through insurance or out of pocket. To provide clarity on affordability, consider the table below:

Pharmacy	Fexofenadine 120mg Price
Shoppers Drug Mart	CAD $XX
Rexall	CAD $XX
Jean Coutu	CAD $XX

Additionally, Canadian e-commerce options for fexofenadine provide decent accessibility for individuals in rural locations. A comparison with US pricing shows that Canadians frequently find more competitive costs at home, highlighting the importance of local healthcare accessibility.

This information empowers patients to make informed purchasing decisions, ensuring they access effective treatments for their allergy concerns.

Keywords: fexofenadine pricing Canada, pharmacy costs, cross-border pricing comparison

Delivery Locations & Times

City	Region	Delivery Time
Toronto	Ontario	5–7 days
Vancouver	British Columbia	5–7 days
Montreal	Quebec	5–7 days
Calgary	Alberta	5–7 days
Ottawa	Ontario	5–7 days
Edmonton	Alberta	5–7 days
Winnipeg	Manitoba	5–9 days
Halifax	Nova Scotia	5–9 days
Victoria	British Columbia	5–9 days
Regina	Saskatchewan	5–9 days
St. John's	Newfoundland	5–9 days
London	Ontario	5–9 days
Kitchener	Ontario	5–9 days
Saskatoon	Saskatchewan	5–9 days