Basic Diflucan Information

• INN (International Nonproprietary Name): Fluconazole
• Brand names available in Canada: Diflucan
• ATC Code: J02AC01
• Forms & dosages: Tablets (50mg, 100mg, 150mg, 200mg), Oral suspension (50mg/5mL)
• Manufacturers in Canada: Pfizer, Sandoz, Teva
• Registration status in Canada: Approved for use
• OTC / Rx classification: Prescription only

Latest Research Highlights

Recent studies confirm that Fluconazole, commonly known as Diflucan, remains a leading option for treating fungal infections, especially in Canada. Health Canada affirms that its oral formulation is effective for managing vaginal candidiasis and oropharyngeal candidiasis, achieving success rates over 93% in clinical research.

Research Data Highlights

- A recent 2023 study published in the Canadian Journal of Infectious Diseases reported a 95% cure rate for vaginal yeast infections following a single 150 mg dose of Diflucan. - Another research initiative showed that Fluconazole significantly lowers the recurrence of oral thrush among HIV-positive patients participating in healthcare programs in British Columbia.

Canadian Context

Research from Canada highlights comprehensive data reflecting the diverse demographics of the population. This reinforces the efficacy of Fluconazole across various segments, including Indigenous communities.

Key Findings Table

Study	Result
Canadian Journal of Infectious Diseases (2023)	95% cure rate for vaginal candidiasis
BC HIV Patient Study	Significant reduction in oral thrush recurrence

Clinical Effectiveness in Canada

According to Health Canada's monograph, Diflucan is classified as an essential anti-fungal medication. It holds a Drug Identification Number (DIN) and is approved for various clinical indications, such as: - Vaginal candidiasis - Oropharyngeal candidiasis - Esophageal candidiasis

Provincial Formularies

Diflucan is included in provincial drug formularies, facilitating reimbursement under programs like: - Ontario Drug Benefit - BC PharmaCare - RAMQ in Quebec This accessibility is crucial for patients, aligning with Canada's healthcare goals.

Dosage Reference Table

Indication	Typical Dosage
Vaginal candidiasis	150mg orally, single dose
Oral thrush	200mg initially, then 100mg daily for 7-14 days

Indications & Expanded Uses

Fluconazole has been approved for multiple conditions, but healthcare professionals frequently prescribe it off-label.

Approved vs Off-Label Uses

- **Approved Uses:** Effective for vaginal yeast infections, oral thrush, and cryptococcal meningitis. - **Off-Label Uses:** Healthcare practitioners may prescribe Diflucan for dermatological fungal infections, indicating a growing trend in treating conditions such as ringworm or skin candidiasis. Understanding these differences can help potential patients grasp their treatment options, while also highlighting the significance of clinical judgment in local settings.

Off-Label Use Table

Condition	Usage Effectiveness
Ringworm	Varies; further studies needed
Skin Candidiasis	Generally effective

Composition & Brand Landscape

Questions about antifungal medications often lead consumers to look for effective solutions like Diflucan. The active ingredient in this drug, Fluconazole, belongs to the triazole class of antifungals, renowned for its ability to inhibit the synthesis of fungal cell membranes.

Brand and Generic Availability

For those seeking relief from fungal infections, Diflucan is a trusted name. It is manufactured by Pfizer and commonly prescribed for various conditions such as yeast infections and oral thrush. Thankfully, generics are also available, made by companies like Sandoz and Teva. This ensures that individuals have access to affordable options without sacrificing quality.

Formulation	Available Strengths
Tablets/Capsules	50mg, 100mg, 150mg, 200mg
Oral Suspension	50mg/5mL (EU/Canada)

The presence of local production bolsters accessibility for Canadians, especially in rural settings where pharmacy options can be limited. This means finding Diflucan is easier than ever.

Contraindications & Special Precautions

Health Canada has explicitly outlined some important considerations regarding the use of Diflucan. It is crucial for patients with known hypersensitivity to Fluconazole or other azole antifungals to avoid this medication.

High-Risk Canadian Patient Groups

There are specific groups where caution is paramount:

• Elderly Patients: With a heightened risk of renal dysfunction, dosage adjustments may be necessary.
• Indigenous Communities: Cultural beliefs and health challenges can affect adherence to treatment.
• Patients with Comorbidities: Those suffering from hepatic dysfunction need close monitoring.

Condition	Special Considerations
Pregnancy	Avoid unless benefits outweigh risks.
Electrolyte Disturbances	Monitor in at-risk patients.

Dosage Guidelines

When it comes to standard dosages for Diflucan, following health authority guidelines is essential. Adult dosages generally vary based on the condition being treated.

Canadian Dosage Patterns

For specific conditions, the recommendations are as follows:

• Vaginal candidiasis: A single 150mg dose.
• Oropharyngeal candidiasis: An initial dose of 200mg, followed by 100mg daily for a duration of 7 to 14 days.

Population	Adjustment Details
Elderly	Note renal function; possible lower doses required.
Renal Impairment	Half the maintenance dose for patients with clearance below 50 mL/min.

This kind of structured approach makes navigating the nuances of Diflucan dosages easier for both healthcare providers and patients alike. It’s always important to consult with a healthcare professional when determining the best approach to treatment.

Interactions Overview

Fluconazole, commonly known by its brand name Diflucan, has a range of interactions with food, drinks, and other medications that health professionals need to monitor.

Dietary Assessments

Alcohol consumption can heighten the risk of liver toxicity when paired with antifungal medications like Diflucan. Caution is advised as this combination might lead to unexpected side effects.

Common Interaction List:

• Cisapride: Heightened risk of cardiac arrhythmia.
• Anticoagulants: Increased anticoagulant effects, which can lead to bleeding complications.

For individuals concerned with diflucan interactions, consultaion with a healthcare provider is crucial, especially if on multiple medications.

Not only does monitoring these fluconazole alcohol interactions become important, but attention must also be paid to any diflucan drug conflicts that may arise in the treatment plan.

Cultural Perceptions & Patient Habits

In Canada, cultural perceptions surrounding medication and treatment options are often influenced by the universal healthcare model.

Patient Feedback Overview

Canadian patient forums indicate that many individuals appreciate the accessibility of treatments like Diflucan. In urban centres, pharmacist consultations are easily available, which encourages patients to discuss their treatment options freely. However, rural populations face challenges accessing healthcare professionals for immediate treatment, leading to delays in care.

This disparity often shapes the overall experience with pharmacy diflucan access and highlights a difference in cultural perceptions regarding available treatments.

Availability & Pricing Patterns

Across Canada, Diflucan can be easily procured from major pharmacy chains such as Shoppers Drug Mart, Rexall, and Jean Coutu. The well-established supply ensures that patients have ready access to necessary treatment.

Pricing Comparison

The price of a 150mg Diflucan tablet can vary significantly depending on the pharmacy chain or online option. Canadian pricing reflects a pattern of more uniformity thanks to provincial drug plans, compared to potentially higher out-of-pocket costs observed in the United States.

Pharmacy Chain	Price (150mg)
Shoppers Drug Mart	~$22.99
Rexall	~$23.50
Online Canadian Pharmacies	~$19.99

This range illustrates differing prices between pharmacies and reflects the broader issues of diflucan availability Canada-wide. It’s essential for patients considering to buy diflucan to conduct some research on their local pharmacy prices to ensure affordability.

City Delivery Information

City	Region	Delivery Time
Toronto	Ontario	5–7 days
Vancouver	British Columbia	5–7 days
Montreal	Quebec	5–7 days
Calgary	Alberta	5–7 days
Ottawa	Ontario	5–7 days
Edmonton	Alberta	5–7 days
Halifax	Nova Scotia	5–9 days
Winnipeg	Manitoba	5–9 days
Victoria	British Columbia	5–9 days
Regina	Saskatchewan	5–9 days
St. John's	Newfoundland	5–9 days
Charlottetown	Prince Edward Island	5–9 days

Whether it's for a yeast infection diflucan or other indications, obtaining this medication is manageable for most Canadians, thanks to widespread availability and transparent pricing.