Basic Cardizem Information

• International Nonproprietary Name (INN): Diltiazem
• Brand names available in Canada: Cardizem, Cardizem CD/LA, Cartia XT, Dilacor XR, Matzim LA, Taztia XT, Tiazac, Dilt-CD, Diltia XT, Dilt-XR, Diltzac, Tiadylt ER
• ATC Code: C08DB01
• Forms & dosages: Tablets (30, 60, 90, 120 mg), Extended-release capsules & tablets (60, 90, 120, 180, 240, 300, 360, 420 mg), Injectable (hospital use)
• Manufacturers in Canada: Bausch Health, Mylan, Teva, Sun Pharma, Actavis, Pfizer
• Registration status in Canada: Prescription-only (Rx)
• OTC / Rx classification: Prescription Only (Rx)

Latest Research Highlights

Recent clinical studies from Canada and around the world have shown promising outcomes regarding the use of Diltiazem. Between 2022 and 2025, several key trials focused on efficacy, side effects, and outcomes for patients using this medication for chronic conditions like angina and hypertension. A comparison of findings from various studies is summarized below, with *Canadian results highlighted in bold*:

Study	Efficacy	Side Effects	Patient Outcomes
Canadian Clinical Trial 2022	80% improvement in angina symptoms	Headaches, minor edema in 10% of patients	70% reported improved quality of life
International Study 2023	65% improvement in hypertension control	Dizziness, fatigue	60% adherence rate over 6 months
Canadian Study 2025	75% effective in long-term angina management	Minimal adverse effects reported	80% of patients satisfied with treatment

Research data indicate that Diltiazem serves a pivotal role in managing conditions prevalent in Canadian healthcare systems, such as *angina* and *hypertension*. With an increasing trend towards recognizing its effectiveness, patients remain hopeful about Diltiazem as a reliable treatment option.

Clinical Effectiveness in Canada

Health Canada’s approval process ensures that medications like Cardizem meet stringent safety and efficacy standards. Each Cardizem product is assigned a Drug Identification Number (DIN) for easy tracking, which is vital for both healthcare professionals and patients. This ensures transparency and confidence in its use. Provincial drug formularies, including the Ontario Drug Benefit and BC PharmaCare, play a significant role in guiding prescribing practices. By integrating Diltiazem into their formulary listings, provinces uphold the accessibility of this crucial medication for Canadians facing cardiovascular challenges. Diltiazem is widely available through major pharmacy chains like Shoppers Drug Mart and Rexall. This accessibility simplifies the process for patients in need of Diltiazem, ensuring that necessary treatments for angina and hypertension are within reach when prescribed by healthcare providers.

Indications & Expanded Uses

Cardizem is primarily indicated for the treatment of chronic angina and hypertension. Recognized for its versatility, it also has off-label uses, such as managing supraventricular tachyarrhythmias. However, there are specific health conditions where discontinuation of Diltiazem may be recommended. Commonly treated conditions with Diltiazem include: - **Chronic angina** - **Hypertension** - **Supraventricular tachyarrhythmias** Supported by the latest Canadian patient guidelines, the appropriateness of Diltiazem use showcases its effectiveness and integration within treatment plans for various cardiovascular issues. In conclusion, as medical research continues to validate Diltiazem’s reliability, healthcare professionals can be assured of its role in effective management strategies for Canadians. Understanding its indications and the importance of ongoing patient assessment ensures optimal results.

Composition & Brand Landscape

The active ingredient in Cardizem is Diltiazem, an effective calcium channel blocker known for its ability to dilate blood vessels and reduce heart workload. In Canada, several brand names encompass various formulations of Diltiazem: - **Cardizem** - **Cartia XT** - **Dilacor XR** - **Tiazac** - **Tiadylt ER** These are offered in numerous packaging forms, ensuring patients receive their required dosages, including immediate-release tablets and extended-release capsules. Additionally, generic alternatives are widely available, providing further accessibility across Canada. It is crucial for patients to consult their healthcare provider regarding the most fitting formulation for their needs, keeping in mind that proper dosages and compliance are key for effective treatment with Diltiazem.

Contraindications & Special Precautions

It's essential to consider both absolute and relative contraindications for Diltiazem as outlined by Health Canada. Understanding these factors assists in ensuring patient safety. Absolute contraindications include: - **Severe hypotension** - **Second- or third-degree AV block (without pacemaker)** - **Sick sinus syndrome (without pacemaker)** - **Acute myocardial infarction with pulmonary congestion** - **Known allergy to Diltiazem or any of its excipients** Relative contraindications that require cautious use include: - **Congestive heart failure** - **Liver or kidney impairment** - **Advanced age** - **Use with beta-blockers (increased risk of bradycardia or AV block)** Special attention should also be directed to high-risk groups, such as the elderly and those with comorbidities. By adhering to these precautions, healthcare professionals can significantly enhance patient safety outcomes while managing treatment plans effectively.

Interactions Overview

When dealing with medications, understanding drug-food interactions is crucial for safety and efficacy. A prime example is grapefruit juice, which can significantly increase the concentration of certain drugs in the bloodstream, including Cardizem (diltiazem). This can lead to heightened side effects such as bradycardia or hypotension.

Health Canada has flagged various drug interactions, specifically highlighting the combination of diltiazem with other medications like beta-blockers. Such combinations may amplify the risk of bradycardia or even result in heart block, conditions that require careful monitoring. This is particularly relevant to Canadian patients who may be prescribed multiple medications for chronic conditions.

Patient education becomes essential regarding these interactions. Clear guidance about when and how to take Cardizem, including any food precautions, can empower patients. For instance, avoiding grapefruit juice and discussing all medications being taken may help to mitigate risks and improve treatment outcomes.

Cultural Perceptions & Patient Habits

Canadian forums, such as Reddit Canada, provide a window into how patients perceive Cardizem. Many users share experiences that vary widely between urban and rural settings. Urban dwellers often report better access to pharmacies and healthcare providers, leading to proactive management of their conditions. Conversely, those in remote areas express concerns about medication availability and reliance on telemedicine, which has become increasingly vital.

Access to pharmacies in these rural regions presents a challenge. The limited availability of personal healthcare practitioners may lead to delays in medication refills, impacting patient adherence. Canada's universal healthcare system plays a significant role in shaping patient views. Many feel reassured that basic healthcare services, including medication access, are covered, which encourages adherence to prescribed medication regimens like Cardizem.

Availability & Pricing Patterns

In Canada, major pharmacy chains such as Shoppers Drug Mart, Rexall, Jean Coutu, and London Drugs implement various pricing strategies for Diltiazem branded products like Cardizem. Price variations can be influenced by promotions, local pharmacy pricing policies, and availability.

However, challenges persist concerning online pharmacies and provincial regulations. Patients often face restrictions on purchasing medications legally from online sources, which can limit options for those seeking more affordable prices. Additionally, a comparison with the US market reveals notable price disparities. Many Canadians often seek cross-border deals for Diltiazem medications, typically finding that prices south of the border are lower, prompting discussions about importing medications for personal use.

Comparable Medicines and Preferences

In the realm of blood pressure management and angina treatment, Cardizem (diltiazem) faces competition from other calcium channel blockers like Amlodipine, Verapamil, and Nifedipine. Each of these alternatives carries its unique set of indications and side effects.

Medicine	Indication	Side Effects	Patient Preference
Diltiazem (Cardizem)	Angina, Hypertension	Headache, Edema	Moderate
Amlodipine	Hypertension	Swelling, Fatigue	High
Verapamil	Supraventricular tachycardia	Constipation, Dizziness	Low
Nifedipine	Hypertension	Flushing, Rash	Moderate

Patients may weigh the pros and cons of Diltiazem versus its alternatives. For instance, while diltiazem is beneficial in managing angina and hypertension, some individuals may prefer alternatives that sport fewer side effects or easier administration schedules. These individual preferences are crucial in determining which medication patients feel most comfortable with and compliant in taking.

FAQ Section

Patients often have common questions regarding Cardizem (diltiazem). Here are some frequently asked questions along with concise answers:

• Can I take Cardizem with food?
  Yes, Cardizem can be taken with or without food; however, it’s important to avoid grapefruit juice.
• What should I do if I miss a dose?
  If a dose is missed, take it as soon as you remember. If it's close to your next dose, skip the missed dose; do not double up.
• What are the long-term effects?
  Long-term use can lead to side effects such as dizziness and swelling. Regular monitoring by a healthcare provider is advised.

These queries highlight the importance of patient-informed conversations surrounding Cardizem and its implications for daily living and healthcare management in Canada.

Guidelines for Proper Use

When using Diltiazem, particularly under the brand Cardizem, it's crucial to get things right. Many people wonder, "What if I miss a dose?" If a dose is forgotten, take it as soon as you remember. But if it's almost time for the next dose, skip the missed one—never double up! This helps to prevent overdose risks, such as severe hypotension or bradycardia.

Adhering to Diltiazem treatment is key for managing conditions like hypertension and angina effectively. Patients are encouraged to set reminders or use pill organizers to stay on track. Regular monitoring of symptoms is essential. That means keeping an eye on blood pressure and heart rate, and reporting any unusual side effects or changes. A quick chat with healthcare providers can help tailor the best approach for personal health needs.

Following provincial health authority guidelines is not just important but essential. Each province may have specific rules about prescriptions and dosing that align with local health standards. This reinforces the need for patient education and awareness in medication management.

Conclusion

In summary, Diltiazem plays a vital role in managing chronic conditions across Canada, especially for heart health. Patient education surrounding Cardizem cannot be overstated—understanding interactions, for instance, can prevent complications. It's equally important to promote accessible healthcare to ensure everyone benefits from appropriate treatment options.

Therefore, it's a strong recommendation for patients to consult healthcare providers for tailored advice regarding Diltiazem. Whether it’s about dosage changes or possible interactions with other medications, don’t hesitate to reach out. Taking care of health is an ongoing conversation that deserves the right attention.

City	Region	Delivery time
Toronto	Ontario	5–7 days
Vancouver	British Columbia	5–7 days
Montreal	Quebec	5–7 days
Calgary	Alberta	5–7 days
Ottawa	Ontario	5–7 days
Edmonton	Alberta	5–7 days
Winnipeg	Manitoba	5–7 days
Halifax	Nova Scotia	5–9 days
Victoria	British Columbia	5–9 days
Regina	Saskatchewan	5–9 days
Saskatoon	Saskatchewan	5–9 days
St. John's	Newfoundland and Labrador	5–9 days
London	Ontario	5–9 days
Kitchener	Ontario	5–9 days
Chatham	Ontario	5–9 days